Tramadol is an oral pain reliever that is used to treat moderate to moderately severe pain. It acts in the brain to affect how your body feels and responds to change, similar to opioid (narcotic) analgesics. Tramadol is a narcotic-like pain reliever that is taken orally to treat moderate to severe pain in adults. This drug's extended-release tablet formulation is intended to treat moderate to severe chronic pain that requires therapy around the clock.